Your team decides. The agents do everything in between.
Pharma contracting is broken in two places: at intake, where the business navigates forms, categories, and systems; and in execution, where a packet of contracts crosses multiple functions, over email, for months.
ContractSphere runs the whole cycle with AI agents, on top of the stack you already own: intake in plain English, the packet read as one and linked to related agreements, agents reviewing in parallel, and decisions with your experts.
Requesters never fill a form. Reviewers never read every page of every document. Platform auto detects, extracts and fills. Agents read, cross-reference, and surface findings with evidence attached. What remains is decisions.
Waiting and first-pass review typically consume half of contract cycle time. Agents run the first pass the moment a request lands, so reviewers start from findings, not from page one. And status lives in the platform, not in follow-up emails.
Renewals, escalators, and rebates surface before they cost money. Contract volume grows without headcount growing with it.
Illustrative model, your inputs, assumptions visible.
Every agreement pharma actually signs, clinical to commercial, understood on install.
Clinical Trial Agreements · Quality Agreements · Pharmacovigilance · Material Transfer · HCP Consulting
Three structural realities of Life Sciences contracting, and the part of the platform built to resolve each one.
The packet a contract travels in, the ecosystem of agreements it lives under, and the trigger map of companion agreements its type demands. One review reads the whole packet, new documents auto-link to their governing agreements with effective terms surfaced in context. And when a companion is missing, expired, or doesn't cover the scope, it's flagged at intake, not at signature.
A punch-out catalog, a sourcing request, or the counterparty's paper: every shape of request enters the same intake, and the platform classifies each by regulatory shape, not just by value and type. A CTA implies a packet; GxP scope implies a quality agreement. Every request is checked against existing masters, with approved suppliers offered at the point of choice, enabling category strategy right where decisions happen. And when the request amends something already signed, it enters pre-classified: linked to its parent agreement, reviewed against both the last executed copy and the agreements it lives under.
The actual product, step by step, from a one-line request to vendor upload, auto-linking, multi-agent review, and a fully drafted system-of-record entry. Real screens, sandbox data.
Eleven specialist reviewers (legal, quality, privacy, finance, safety, and more) are scoped by context: they review the documents and linked agreements and surface findings for human SMEs to review and decide. When your compliance posture changes, the function owner retrains its agent in natural language or training documents — and that enterprise context becomes the agent's topmost instruction, applied at highest weight in every review from that moment on.
Clause-level risk, redlines, fallback positions, playbook adherence. Cuts senior-counsel hours on boilerplate.
Quality Agreement scope, GxP coverage, change-control obligations, supplier-audit standards, inspection readiness.
Pricing, payment terms, indemnity caps, revenue recognition flags. Protects DPO, margin, and rev-rec timing.
Ask anything across your contracts. Deterministic engines calculate, and a grounding gate verifies every hard fact against the source data before it reaches you. When a value doesn't exist in your records, it says so plainly.
Horizontal tools ship as platforms; all three have to be built onto them.
| Capability | Horizontal orchestration tools(Zip, Oro Labs, Tonkean, Omnea) | ContractSphereBuilt for Life Sciences |
|---|---|---|
| User experience | ||
| Intakecatalog · formless · SOW · document-in | adaptive forms | formless intake |
| Integrationsintake → review → routing → sync | ||
| The differentiators | ||
| Connected-contract understandingauto-links to governing agreements · surfaces effective terms · flags missing masters · pharma triggers→ 01 · Connected-contract understanding | ||
| Life Sciences contract coverageCTA · CMA · QAA · PVA · HCP · Sunshine Act · GxP · Global Trade · native taxonomy→ 02 · Pharma domain depth | ||
| Agentic contract reviewout-of-box, domain-aware→ 03 · Contextualized review | ||
| Operational intelligenceprotocol rollups · batch capacity · aggregate exposure | ||
Your CLM stays the system of record. Your ERP stays the ledger. ContractSphere is the layer between that understands what they're holding.
Two ways to run. Same rules for your data.
ContractSphere deploys into your own Azure tenant. Your organization's security policies, network controls, and monitoring apply automatically. Your keys, your access grants, revocable anytime.
Your data is isolated and encrypted per tenant, never commingled.
The business wants velocity but has settled for the current pace. Plans get padded to absorb long lead times, and that quiet padding is the real cost: working capital, milestones, and program velocity written off as normal. Execution speed is trapped inside cross-team reviews, and your team carries the accountability without the ownership.
ContractSphere breaks that status quo: agents run the first pass of every review, and you get one place to see and manage the whole cycle. The cycle becomes visible, measurable, and actionable.
The four-week product-fit evaluation is built to be your proof: a go/no-go readout on your own documents, on our platform, before IT is involved or anyone's asked to change how they work.
The cycle has been waiting for someone to own the change. It doesn't have to keep waiting.
"I spent ten years in pharma, most recently leading G&A IT and enterprise automation at a public biotech, where I lived this problem. I couldn't find the right solution. So I built ContractSphere."
Same category, procurement orchestration, but built vertically for Life Sciences. Horizontal orchestration tools are built for general procurement and ship as configurable platforms you build pharma context onto; ContractSphere ships it in: 30+ contract types, 11 pharma-trained domain agents, and connected-contract understanding out of the box. It coexists with, and does not replace, your CLM, ERP, and S2P suites.
No. Your CLM stays the system of record for storage, e-signature, and renewals. ContractSphere.ai is the intelligence and orchestration layer above it: intake, auto-linking, multi-agent review, and routing.
It's designed to sit above your CLM. If you don't have one yet, that's a deployment conversation we have directly — the platform still runs intake, review, and orchestration through to signature.
Each domain agent is a Digital Employee, not a generic bot. It reports into the manager of its function, who trains it on their playbook, SOPs, and risk appetite and signs off on its work. Every review runs with a human in the loop: the agent surfaces its findings with reasoning attached and never decides.
It reads context at two levels: the packet (a main agreement with its annexes and exhibits) and the ecosystem (how it relates to MSAs, DPAs, QAAs, and SOWs). Reviews are cross-document by default, and a missing, expired, or insufficient master is flagged before review begins.
As first-class intake, not a special case. An amendment arrives pre-classified and linked to its parent, and review runs two comparisons at once: against the last executed version (what changed) and against the linked agreements it lives under (what the change breaks or triggers). In clinical operations amendments outnumber new agreements — the platform is built for that ratio.
30+ Life Sciences types out of the box: CDA/NDA, MSA, SOW, CTA, CMA, QAA, PVA, SDEA, MSSA, ISR, MTA, and more, each with its own field model.
Yes: run on our Multi-Tenant SaaS, isolated and encrypted per tenant, or Bring Your Own Cloud on Microsoft Azure, where the application runs inside your own subscription and your security perimeter is the perimeter. Deployment is chosen in the design-partnership charter, and a BYOC choice means technical go-live lands in your own tenant. Deployment details: Security page →
It starts with a four-week product-fit evaluation: a small set of your anonymized contracts on our platform, standard logins, no IT involvement, ending in a go/no-go readout on your own documents. If it's a go, the paid design partnership begins: we connect your SSO and systems, load ~100 contracts in your own nomenclature, and finish at technical go-live. Your license activates there, with the partnership fee credited in full against it. Business rollout then runs at your pace. Details on the design-partner page.
Two deployment models: Multi-Tenant SaaS, where your data is isolated and encrypted per tenant and evaluation sets are deleted if you don't continue, or Bring Your Own Cloud on Microsoft Azure, where the application runs inside your subscription, so your security perimeter is the perimeter. Contract content, embeddings, and model traffic are never used to train third-party models. Full controls, access model, and audit posture: Security page →
Enterprise SSO via Okta, Microsoft Entra (MSAL / Azure AD), and Google Workspace, with SCIM 2.0 provisioning and role-based access control.